STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpsPPsort-B: Cytoplasmic, score:8.87; COG0228 Ribosomal protein S16; HMMPfam:IPR000307; BlastProDom:IPR000307; Gene3D:IPR000307; HMMPanther:IPR000307; HMMTigr:IPR000307; superfamily:IPR000307; K02959 small subunit ribosomal protein S16. (81 aa)    
Predicted Functional Partners:
rpsL
Small subunit ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 0.997
rpsJ
Small subunit ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
 0.997
rpsG
Small subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
 0.996
rpsZ
Small subunit ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
   
 0.996
rpsK
Small subunit ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
 0.996
rpsI
Psort-B: Cytoplasmic, score:8.87; COG0103 Ribosomal protein S9; HMMPfam:IPR000754; BlastProDom:IPR000754; Gene3D:IPR014721; HMMPanther:IPR000754; ScanRegExp:IPR000754; K02996 small subunit ribosomal protein S9.
  
 0.996
rpsB
Psort-B: Cytoplasmic, score:8.87; COG0052 Ribosomal protein S2; HMMPfam:IPR001865; FPrintScan:IPR001865; HMMPanther:IPR005706; HMMTigr:IPR005706; ScanRegExp:IPR001865; superfamily:IPR001865; K02967 small subunit ribosomal protein S2.
  
 0.996
rpsO
Small subunit ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
 0.996
rplS
Large subunit ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.996
rpsF
Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 0.996
Your Current Organism:
Eubacterium eligens
NCBI taxonomy Id: 515620
Other names: Eubacterium eligens ATCC 27750, [. eligens ATCC 27750, [Eubacterium] eligens ATCC 27750
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.