STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACR72828.1Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. (412 aa)    
Predicted Functional Partners:
ybeY
Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
 
 0.886
rplU
Large subunit ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.886
rplQ
Psort-B: Cytoplasmic, score:8.87; COG0203 Ribosomal protein L17; HMMPfam:IPR000456; BlastProDom:IPR000456; Gene3D:IPR000456; HMMPanther:IPR000456; HMMTigr:IPR000456; superfamily:IPR000456; K02879 large subunit ribosomal protein L17.
  
 
 0.884
guaB
Malate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.884
rplO
Large subunit ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.874
rplK
Large subunit ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.872
ACR72897.1
Long-chain fatty-acid-CoA ligase; Psort-B: Cytoplasmic, score:9.98; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; HMMPfam:IPR000873; ScanRegExp:IPR000873; K01897 long-chain fatty-acid-CoA ligase.
  
   0.871
rplM
Large subunit ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.868
rpsQ
Small subunit ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.862
rplC
Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.848
Your Current Organism:
Eubacterium eligens
NCBI taxonomy Id: 515620
Other names: Eubacterium eligens ATCC 27750, [. eligens ATCC 27750, [Eubacterium] eligens ATCC 27750
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.