STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtur_0690PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: dth:DICTH_0529 anthranilate synthase component I. (465 aa)    
Predicted Functional Partners:
Dtur_0691
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: dth:DICTH_0530 anthranilate synthase component II.
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 0.999
Dtur_0693
PFAM: Indole-3-glycerol phosphate synthase; KEGG: dth:DICTH_0532 indole-3-glycerol phosphate synthase.
 
 0.999
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: dth:DICTH_0533 N-(5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
  
 0.988
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.987
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.985
Dtur_1641
PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: dth:DICTH_1531 P-protein.
 
 
 0.965
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.952
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
 0.840
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
  
 0.765
Your Current Organism:
Dictyoglomus turgidum
NCBI taxonomy Id: 515635
Other names: D. turgidum DSM 6724, Dictyoglomus turgidum DSM 6724, Dictyoglomus turgidum str. DSM 6724, Dictyoglomus turgidum strain DSM 6724
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