STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (255 aa)    
Predicted Functional Partners:
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.959
Dtur_1221
KEGG: dth:DICTH_1096 membrane protein.
 
     0.818
Dtur_1214
TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: dth:DICTH_1089 biotin-[acetyl-CoA-carboxylase] ligase.
  
    0.797
Dtur_1217
KEGG: dth:DICTH_1092 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region.
       0.649
Dtur_1219
KEGG: dth:DICTH_1094 hypothetical protein.
       0.613
Dtur_1216
KEGG: dth:DICTH_1090 hypothetical protein.
       0.612
Dtur_1218
Adenylate/guanylate cyclase with Chase sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: dth:DICTH_1093 adenylate cyclase.
       0.612
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.574
Dtur_1222
PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: dth:DICTH_1097 5,10-methenyltetrahydrofolate synthetase.
       0.553
hslO
Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
  
    0.436
Your Current Organism:
Dictyoglomus turgidum
NCBI taxonomy Id: 515635
Other names: D. turgidum DSM 6724, Dictyoglomus turgidum DSM 6724, Dictyoglomus turgidum str. DSM 6724, Dictyoglomus turgidum strain DSM 6724
Server load: low (26%) [HD]