SIT74865.1 protein (Pontibaca methylaminivorans)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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SIT74865.1

Putative rhamnosyl transferase. (274 aa)

Predicted Functional Partners:

SIT87120.1

0.656

SIT83061.1

0.612

SIT81986.1

0.610

SIT77996.1

0.576

SIT84476.1

0.566

SIT85303.1

0.555

SIT76408.1

0.545

SIT84058.1

0.536

SIT84744.1

0.509

SIT81097.1

0.505

Your Current Organism:

Pontibaca methylaminivorans

NCBI taxonomy Id: 515897
Other names: DSM 21219, KCTC 22497, P. methylaminivorans, Pontibaca methylaminivorans Kim et al. 2010, alpha proteobacterium GRP21, alpha proteobacterium PH34, strain GRP21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SIT74865.1	SIT76408.1	SAMN05421849_0225	SAMN05421849_0508	Putative rhamnosyl transferase.	Glycosyl transferase family 2; Non-canonical start codon; manually curated.	0.545
SIT74865.1	SIT77996.1	SAMN05421849_0225	SAMN05421849_0871	Putative rhamnosyl transferase.	Hypothetical protein.	0.576
SIT74865.1	SIT81097.1	SAMN05421849_0225	SAMN05421849_1424	Putative rhamnosyl transferase.	Glycosyltransferase involved in cell wall bisynthesis.	0.505
SIT74865.1	SIT81986.1	SAMN05421849_0225	SAMN05421849_1593	Putative rhamnosyl transferase.	Hypothetical protein.	0.610
SIT74865.1	SIT83061.1	SAMN05421849_0225	SAMN05421849_1833	Putative rhamnosyl transferase.	Pectate lyase superfamily protein.	0.612
SIT74865.1	SIT84058.1	SAMN05421849_0225	SAMN05421849_2036	Putative rhamnosyl transferase.	Membrane protein involved in the export of O-antigen and teichoic acid.	0.536
SIT74865.1	SIT84476.1	SAMN05421849_0225	SAMN05421849_2122	Putative rhamnosyl transferase.	Hypothetical protein.	0.566
SIT74865.1	SIT84744.1	SAMN05421849_0225	SAMN05421849_2176	Putative rhamnosyl transferase.	Transcriptional regulator, TetR family.	0.509
SIT74865.1	SIT85303.1	SAMN05421849_0225	SAMN05421849_2294	Putative rhamnosyl transferase.	Hypothetical protein.	0.555
SIT74865.1	SIT87120.1	SAMN05421849_0225	SAMN05421849_2577	Putative rhamnosyl transferase.	Glycosyltransferase involved in cell wall bisynthesis.	0.656
SIT76408.1	SIT74865.1	SAMN05421849_0508	SAMN05421849_0225	Glycosyl transferase family 2; Non-canonical start codon; manually curated.	Putative rhamnosyl transferase.	0.545
SIT76408.1	SIT77996.1	SAMN05421849_0508	SAMN05421849_0871	Glycosyl transferase family 2; Non-canonical start codon; manually curated.	Hypothetical protein.	0.718
SIT76408.1	SIT81986.1	SAMN05421849_0508	SAMN05421849_1593	Glycosyl transferase family 2; Non-canonical start codon; manually curated.	Hypothetical protein.	0.553
SIT76408.1	SIT85303.1	SAMN05421849_0508	SAMN05421849_2294	Glycosyl transferase family 2; Non-canonical start codon; manually curated.	Hypothetical protein.	0.633
SIT77996.1	SIT74865.1	SAMN05421849_0871	SAMN05421849_0225	Hypothetical protein.	Putative rhamnosyl transferase.	0.576
SIT77996.1	SIT76408.1	SAMN05421849_0871	SAMN05421849_0508	Hypothetical protein.	Glycosyl transferase family 2; Non-canonical start codon; manually curated.	0.718
SIT77996.1	SIT83061.1	SAMN05421849_0871	SAMN05421849_1833	Hypothetical protein.	Pectate lyase superfamily protein.	0.658
SIT77996.1	SIT84058.1	SAMN05421849_0871	SAMN05421849_2036	Hypothetical protein.	Membrane protein involved in the export of O-antigen and teichoic acid.	0.449
SIT77996.1	SIT85303.1	SAMN05421849_0871	SAMN05421849_2294	Hypothetical protein.	Hypothetical protein.	0.738
SIT81097.1	SIT74865.1	SAMN05421849_1424	SAMN05421849_0225	Glycosyltransferase involved in cell wall bisynthesis.	Putative rhamnosyl transferase.	0.505

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Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.818

expected number of edges:

20

PPI enrichment p-value:

0.0113

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019470

4-hydroxyproline catabolic process

2 of 2

2.56

1.03

0.0133

GO:0046653

Tetrahydrofolate metabolic process

3 of 18

1.78

0.95

0.0133

GO:1901606

Alpha-amino acid catabolic process

3 of 28

1.59

0.9

0.0133

GO:0006575

Cellular modified amino acid metabolic process

5 of 102

1.25

0.87

0.0067

GO:0046416

D-amino acid metabolic process

2 of 6

2.08

0.87

0.0231

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008115

Sarcosine oxidase activity

3 of 9

2.08

1.58

0.00085

GO:0016645

Oxidoreductase activity, acting on the CH-NH group of donors

4 of 33

1.64

1.42

0.00074

GO:0016491

Oxidoreductase activity

9 of 515

0.8

0.69

0.00034

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1927

GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1, and Sarcosine oxidase, delta subunit family

4 of 24

1.78

1.79

0.00013

CL:1922

Mixed, incl. GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1, and NADH:flavin oxidoreductase / NADH oxidase family

5 of 50

1.56

1.63

0.00011

CL:1929

FAD dependent oxidoreductase central domain, and Sarcosine oxidase activity

3 of 18

1.78

1.3

0.0022

CL:1699

Mixed, incl. Carbon metabolism, and Oxidoreductase activity, acting on the CH-NH group of donors

7 of 181

1.15

0.00011

CL:5479

Mixed, incl. Alkylhydroperoxidase AhpD core, and EF-hand, calcium binding motif

2 of 6

2.08

0.92

0.0187

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00472

D-Arginine and D-ornithine metabolism

2 of 3

2.39

1.17

0.0071

map00330

Arginine and proline metabolism

3 of 57

1.28

0.73

0.0203

map01100

Metabolic pathways

11 of 1641

0.39

0.31

0.0071

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

10 of 1255

0.46

0.34

0.0135

GOCC:0005622

Intracellular

11 of 1613

0.39

0.3

0.0135

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF07992

Pyridine nucleotide-disulphide oxidoreductase

4 of 16

1.96

1.99

8.26e-05

PF13510

2Fe-2S iron-sulfur cluster binding domain

3 of 7

2.19

1.71

0.00052

PF04324

BFD-like [2Fe-2S] binding domain

2 of 2

2.56

1.27

0.0047

PF08669

Glycine cleavage T-protein C-terminal barrel domain

3 of 19

1.76

1.19

0.0038

PF01571

Aminomethyltransferase folate-binding domain

3 of 18

1.78

1.19

0.0038

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR041117

SoxA, A3 domain

5 of 5

2.56

4.02

1.96e-08

IPR041854

BFD-like [2Fe-2S]-binding domain superfamily

4 of 4

2.56

3.17

1.04e-06

IPR036188

FAD/NAD(P)-binding domain superfamily

7 of 80

1.5

2.15

3.98e-07

IPR042204

2Fe-2S iron-sulfur cluster binding domain, N-terminal

3 of 5

2.34

1.91

0.00025

IPR023753

FAD/NAD(P)-binding domain

4 of 24

1.78

1.7

0.00022

(more ...)

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