STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT82421.1Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. (410 aa)    
Predicted Functional Partners:
SIT82425.1
HflC protein.
 
 0.999
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.995
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.846
SIT82429.1
Hypothetical protein.
       0.839
SIT83397.1
Zinc protease; Belongs to the peptidase M16 family.
  
 0.760
SIT82416.1
NADPH-glutathione reductase.
  
   0.758
SIT82038.1
Membrane associated serine protease, rhomboid family.
   
 0.745
SIT82897.1
Rhomboid family protein.
   
 0.745
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.724
SIT78840.1
Predicted Zn-dependent peptidase; Belongs to the peptidase M16 family.
   
 0.720
Your Current Organism:
Pontibaca methylaminivorans
NCBI taxonomy Id: 515897
Other names: DSM 21219, KCTC 22497, P. methylaminivorans, Pontibaca methylaminivorans Kim et al. 2010, alpha proteobacterium GRP21, alpha proteobacterium PH34, strain GRP21
Server load: low (28%) [HD]