SIT84393.1 protein (Pontibaca methylaminivorans)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

SIT84393.1

Hypothetical protein. (91 aa)

Predicted Functional Partners:

SIT84388.1

0.773

SIT84098.1

0.724

lcdH

0.686

SIT75835.1

0.643

SIT84086.1

0.641

SIT75723.1

0.627

SIT82522.1

0.619

SIT77646.1

0.617

SIT75651.1

0.598

SIT75390.1

0.594

Your Current Organism:

Pontibaca methylaminivorans

NCBI taxonomy Id: 515897
Other names: DSM 21219, KCTC 22497, P. methylaminivorans, Pontibaca methylaminivorans Kim et al. 2010, alpha proteobacterium GRP21, alpha proteobacterium PH34, strain GRP21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SIT75390.1	SIT75723.1	SAMN05421849_0319	SAMN05421849_0375	[Acyl-carrier-protein] S-malonyltransferase.	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.797
SIT75390.1	SIT75835.1	SAMN05421849_0319	SAMN05421849_0394	[Acyl-carrier-protein] S-malonyltransferase.	Phosphate butyryltransferase.	0.553
SIT75390.1	SIT82522.1	SAMN05421849_0319	SAMN05421849_1717	[Acyl-carrier-protein] S-malonyltransferase.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.	0.643
SIT75390.1	SIT84086.1	SAMN05421849_0319	SAMN05421849_2041	[Acyl-carrier-protein] S-malonyltransferase.	Natural product biosynthesis luciferase-like monooxygenase domain-containing protein.	0.656
SIT75390.1	SIT84098.1	SAMN05421849_0319	SAMN05421849_2043	[Acyl-carrier-protein] S-malonyltransferase.	Acyl transferase domain-containing protein.	0.999
SIT75390.1	SIT84393.1	SAMN05421849_0319	SAMN05421849_2107	[Acyl-carrier-protein] S-malonyltransferase.	Hypothetical protein.	0.594
SIT75390.1	lcdH	SAMN05421849_0319	SAMN05421849_2239	[Acyl-carrier-protein] S-malonyltransferase.	Carnitine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.	0.825
SIT75651.1	SIT75723.1	SAMN05421849_0363	SAMN05421849_0375	Reductase C-terminal.	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.666
SIT75651.1	SIT75835.1	SAMN05421849_0363	SAMN05421849_0394	Reductase C-terminal.	Phosphate butyryltransferase.	0.605
SIT75651.1	SIT77646.1	SAMN05421849_0363	SAMN05421849_0786	Reductase C-terminal.	Ferredoxin, 2Fe-2S.	0.920
SIT75651.1	SIT84086.1	SAMN05421849_0363	SAMN05421849_2041	Reductase C-terminal.	Natural product biosynthesis luciferase-like monooxygenase domain-containing protein.	0.719
SIT75651.1	SIT84098.1	SAMN05421849_0363	SAMN05421849_2043	Reductase C-terminal.	Acyl transferase domain-containing protein.	0.736
SIT75651.1	SIT84393.1	SAMN05421849_0363	SAMN05421849_2107	Reductase C-terminal.	Hypothetical protein.	0.598
SIT75723.1	SIT75390.1	SAMN05421849_0375	SAMN05421849_0319	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	[Acyl-carrier-protein] S-malonyltransferase.	0.797
SIT75723.1	SIT75651.1	SAMN05421849_0375	SAMN05421849_0363	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Reductase C-terminal.	0.666
SIT75723.1	SIT75835.1	SAMN05421849_0375	SAMN05421849_0394	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Phosphate butyryltransferase.	0.995
SIT75723.1	SIT82522.1	SAMN05421849_0375	SAMN05421849_1717	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.	0.914
SIT75723.1	SIT84098.1	SAMN05421849_0375	SAMN05421849_2043	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Acyl transferase domain-containing protein.	0.879
SIT75723.1	SIT84393.1	SAMN05421849_0375	SAMN05421849_2107	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Hypothetical protein.	0.627
SIT75723.1	lcdH	SAMN05421849_0375	SAMN05421849_2239	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Carnitine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.	0.649

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

25

PPI enrichment p-value:

7.3e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 92

1.32

2.29

4.91e-12

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

10 of 37

1.68

3.81

1.21e-13

GO:0003735

Structural constituent of ribosome

10 of 49

1.56

3.21

7.30e-13

GO:0000049

tRNA binding

5 of 19

1.67

2.13

6.14e-06

GO:0003676

Nucleic acid binding

11 of 225

0.93

1.11

6.14e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044391

Ribosomal subunit

6 of 12

1.94

3.67

2.03e-09

GO:0005840

Ribosome

10 of 53

1.52

3.08

7.12e-13

GO:0015935

Small ribosomal subunit

3 of 6

1.94

1.87

0.00015

GO:0015934

Large ribosomal subunit

3 of 6

1.94

1.87

0.00015

GO:0005622

Intracellular anatomical structure

11 of 682

0.45

0.39

0.00015

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:64

Ribosome, and Translational elongation

11 of 72

1.43

2.78

1.87e-13

CL:68

Ribosome, and Elongation factor

9 of 61

1.41

2.45

1.49e-10

CL:72

Ribosome

5 of 28

1.5

1.8

1.36e-05

CL:154

rRNA binding, and Elongation factor Tu GTP binding domain

4 of 18

1.59

1.68

9.76e-05

CL:75

Ribosome

4 of 22

1.51

1.5

0.00019

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 52

1.53

3.13

5.28e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044391

Ribosomal subunit

6 of 15

1.85

3.0

6.83e-08

GOCC:0015934

Large ribosomal subunit

4 of 6

2.07

2.65

3.45e-06

GOCC:0005840

Ribosome

7 of 36

1.53

2.37

6.83e-08

GOCC:0022626

Cytosolic ribosome

4 of 10

1.85

2.23

1.26e-05

GOCC:0043229

Intracellular organelle

10 of 171

1.01

1.22

6.83e-08

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 52

1.53

3.1

8.99e-13

KW-0687

Ribonucleoprotein

10 of 52

1.53

3.1

8.99e-13

KW-0820

tRNA-binding

4 of 10

1.85

2.17

1.77e-05

KW-0699

rRNA-binding

6 of 31

1.53

2.15

7.32e-07

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