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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (446 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 0.994
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
     0.801
VC82_1180
Pfam:pfam03301 Tryptophan 2,3-dioxygenase.
 
   
 0.778
VC82_2294
Pfam:pfam03109 ABC1 family.
   
 0.646
VC82_984
Pfam:pfam00368 Hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
   
  
 0.625
VC82_1341
Pfam:pfam13489 Methyltransferase domain.
  
 0.622
VC82_710
Pfam:pfam12847 Methyltransferase domain.
  
 0.622
VC82_1747
N-formylkynurenine (Aryl-) formamidase; Pfam:pfam04199 Putative cyclase.
 
     0.609
VC82_2852
ABC transporter substrate-binding protein; Pfam:pfam09084 NMT1/THI5 like.
  
   
 0.594
VC82_811
Pfam:pfam13489 Methyltransferase domain.
  
 0.587
Your Current Organism:
Muricauda lutaonensis
NCBI taxonomy Id: 516051
Other names: BCRC 17850, KCTC 22339, M. lutaonensis, Muricauda lutaonensis Arun et al. 2009 emend. Hahnke et al. 2016, Muricauda sp. CC-HSB-11, strain CC-HSB-11
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