| node1 | node2 | node1 annotation | node2 annotation | score |
| VC82_1286 | VC82_242 | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Propionyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. | 0.879 |
| VC82_1286 | VC82_2557 | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.921 |
| VC82_1286 | VC82_563 | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.913 |
| VC82_1286 | VC82_92 | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. | 0.464 |
| VC82_1303 | VC82_1603 | Methylmalonyl-CoA epimerase; Pfam:pfam13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. | Pfam:pfam01642 Methylmalonyl-CoA mutase. | 0.979 |
| VC82_1303 | VC82_242 | Methylmalonyl-CoA epimerase; Pfam:pfam13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. | Propionyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. | 0.961 |
| VC82_1603 | VC82_1303 | Pfam:pfam01642 Methylmalonyl-CoA mutase. | Methylmalonyl-CoA epimerase; Pfam:pfam13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. | 0.979 |
| VC82_1603 | VC82_1910 | Pfam:pfam01642 Methylmalonyl-CoA mutase. | Pfam:pfam00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. | 0.421 |
| VC82_1603 | VC82_242 | Pfam:pfam01642 Methylmalonyl-CoA mutase. | Propionyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. | 0.601 |
| VC82_1603 | VC82_2557 | Pfam:pfam01642 Methylmalonyl-CoA mutase. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.420 |
| VC82_1603 | VC82_92 | Pfam:pfam01642 Methylmalonyl-CoA mutase. | Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. | 0.587 |
| VC82_1605 | VC82_242 | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | Propionyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. | 0.835 |
| VC82_1605 | VC82_2557 | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.918 |
| VC82_1605 | VC82_563 | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.848 |
| VC82_1605 | VC82_92 | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. | 0.577 |
| VC82_1910 | VC82_1603 | Pfam:pfam00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. | Pfam:pfam01642 Methylmalonyl-CoA mutase. | 0.421 |
| VC82_1910 | VC82_242 | Pfam:pfam00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. | Propionyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. | 0.610 |
| VC82_1910 | VC82_92 | Pfam:pfam00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. | Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. | 0.444 |
| VC82_242 | VC82_1286 | Propionyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.879 |
| VC82_242 | VC82_1303 | Propionyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. | Methylmalonyl-CoA epimerase; Pfam:pfam13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. | 0.961 |