Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
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kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (242 aa)    
Predicted Functional Partners:
VC82_293
Pfam:pfam00465 Iron-containing alcohol dehydrogenase.
    
 0.981
VC82_2597
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family.
 
  
 0.975
VC82_1861
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.962
VC82_381
KpsF/GutQ family protein; Pfam:pfam01380 SIS domain; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.869
VC82_689
2-dehydro-3-deoxyphosphogluconate aldolase; Pfam:pfam00793 DAHP synthetase I family; Belongs to the KdsA family.
 
   
 0.835
lpxK
Tetraacyldisaccharide 4''''-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.824
VC82_979
Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.820
VC82_294
Pfam:pfam13419 Haloacid dehalogenase-like hydrolase.
       0.818
VC82_2740
UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.808
VC82_296
Hypothetical protein; Pfam:pfam13548 Domain of unknown function (DUF4126).
       0.800
Your Current Organism:
Muricauda lutaonensis
NCBI taxonomy Id: 516051
Other names: BCRC 17850, KCTC 22339, M. lutaonensis, Muricauda lutaonensis Arun et al. 2009 emend. Hahnke et al. 2016, Muricauda sp. CC-HSB-11, strain CC-HSB-11
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