| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VC82_2456 | VC82_2645 | VC82_2456 | VC82_2645 | Pfam:pfam14821 Threonine synthase N terminus. | Threonine aldolase; Pfam:pfam01212 Beta-eliminating lyase. | 0.922 |
| VC82_2456 | VC82_2922 | VC82_2456 | VC82_2922 | Pfam:pfam14821 Threonine synthase N terminus. | Pfam:pfam10369 Small subunit of acetolactate synthase. | 0.443 |
| VC82_2456 | VC82_2923 | VC82_2456 | VC82_2923 | Pfam:pfam14821 Threonine synthase N terminus. | Acetolactate synthase; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. | 0.475 |
| VC82_2456 | VC82_522 | VC82_2456 | VC82_522 | Pfam:pfam14821 Threonine synthase N terminus. | Threonine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | 0.945 |
| VC82_2456 | leuB | VC82_2456 | VC82_2918 | Pfam:pfam14821 Threonine synthase N terminus. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.414 |
| VC82_2645 | VC82_2456 | VC82_2645 | VC82_2456 | Threonine aldolase; Pfam:pfam01212 Beta-eliminating lyase. | Pfam:pfam14821 Threonine synthase N terminus. | 0.922 |
| VC82_2645 | VC82_522 | VC82_2645 | VC82_522 | Threonine aldolase; Pfam:pfam01212 Beta-eliminating lyase. | Threonine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | 0.922 |
| VC82_2645 | glyA | VC82_2645 | VC82_3004 | Threonine aldolase; Pfam:pfam01212 Beta-eliminating lyase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.932 |
| VC82_2922 | VC82_2456 | VC82_2922 | VC82_2456 | Pfam:pfam10369 Small subunit of acetolactate synthase. | Pfam:pfam14821 Threonine synthase N terminus. | 0.443 |
| VC82_2922 | VC82_2923 | VC82_2922 | VC82_2923 | Pfam:pfam10369 Small subunit of acetolactate synthase. | Acetolactate synthase; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. | 0.999 |
| VC82_2922 | VC82_522 | VC82_2922 | VC82_522 | Pfam:pfam10369 Small subunit of acetolactate synthase. | Threonine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | 0.963 |
| VC82_2922 | leuB | VC82_2922 | VC82_2918 | Pfam:pfam10369 Small subunit of acetolactate synthase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.983 |
| VC82_2923 | VC82_2456 | VC82_2923 | VC82_2456 | Acetolactate synthase; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. | Pfam:pfam14821 Threonine synthase N terminus. | 0.475 |
| VC82_2923 | VC82_2922 | VC82_2923 | VC82_2922 | Acetolactate synthase; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. | Pfam:pfam10369 Small subunit of acetolactate synthase. | 0.999 |
| VC82_2923 | VC82_522 | VC82_2923 | VC82_522 | Acetolactate synthase; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. | Threonine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | 0.960 |
| VC82_2923 | leuB | VC82_2923 | VC82_2918 | Acetolactate synthase; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.979 |
| VC82_2972 | VC82_386 | VC82_2972 | VC82_386 | Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphatidylserine synthase; Pfam:pfam01066 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| VC82_2972 | VC82_522 | VC82_2972 | VC82_522 | Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | 0.929 |
| VC82_2972 | glyA | VC82_2972 | VC82_3004 | Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.952 |
| VC82_2972 | trpA | VC82_2972 | VC82_2225 | Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.913 |