Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
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VC82_558Exodeoxyribonuclease III; Pfam:pfam03372 Endonuclease/Exonuclease/phosphatase family. (256 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.926
VC82_1159
Exodeoxyribonuclease III Xth; Pfam:pfam03372 Endonuclease/Exonuclease/phosphatase family.
  
  
 
0.907
VC82_1024
Pfam:pfam00849 RNA pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family.
  
    0.709
VC82_2547
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.671
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.611
VC82_1131
Adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.607
VC82_2687
Pfam:pfam09674 Protein of unknown function (DUF2400).
  
 0.571
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.537
hisB
Pfam:pfam00475 Imidazoleglycerol-phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
  
 
 0.511
VC82_559
Hypothetical protein.
       0.419
Your Current Organism:
Muricauda lutaonensis
NCBI taxonomy Id: 516051
Other names: BCRC 17850, KCTC 22339, M. lutaonensis, Muricauda lutaonensis Arun et al. 2009 emend. Hahnke et al. 2016, Muricauda sp. CC-HSB-11, strain CC-HSB-11
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