| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VC82_1605 | VC82_1939 | VC82_1605 | VC82_1939 | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.412 |
| VC82_1605 | VC82_2557 | VC82_1605 | VC82_2557 | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.918 |
| VC82_1605 | VC82_563 | VC82_1605 | VC82_563 | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.848 |
| VC82_1605 | ackA | VC82_1605 | VC82_562 | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.908 |
| VC82_1939 | VC82_1605 | VC82_1939 | VC82_1605 | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | 0.412 |
| VC82_1939 | VC82_2201 | VC82_1939 | VC82_2201 | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | Lactate utilization protein B/C; Pfam:pfam02589 Uncharacterized ACR, YkgG family COG1556. | 0.463 |
| VC82_1939 | VC82_2557 | VC82_1939 | VC82_2557 | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.446 |
| VC82_1939 | VC82_2847 | VC82_1939 | VC82_2847 | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 2-oxoisovalerate dehydrogenase, E1 subunit; Pfam:pfam00676 Dehydrogenase E1 component. | 0.884 |
| VC82_1939 | VC82_2898 | VC82_1939 | VC82_2898 | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | Transketolase domain-containing protein; Pfam:pfam00676 Dehydrogenase E1 component. | 0.884 |
| VC82_1939 | VC82_563 | VC82_1939 | VC82_563 | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.541 |
| VC82_1939 | ackA | VC82_1939 | VC82_562 | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.830 |
| VC82_2201 | VC82_1939 | VC82_2201 | VC82_1939 | Lactate utilization protein B/C; Pfam:pfam02589 Uncharacterized ACR, YkgG family COG1556. | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.463 |
| VC82_2201 | VC82_563 | VC82_2201 | VC82_563 | Lactate utilization protein B/C; Pfam:pfam02589 Uncharacterized ACR, YkgG family COG1556. | Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.722 |
| VC82_2201 | ackA | VC82_2201 | VC82_562 | Lactate utilization protein B/C; Pfam:pfam02589 Uncharacterized ACR, YkgG family COG1556. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.540 |
| VC82_2367 | ackA | VC82_2367 | VC82_562 | Secondary thiamine-phosphate synthase; Pfam:pfam01894 Uncharacterized protein family UPF0047. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.675 |
| VC82_2557 | VC82_1605 | VC82_2557 | VC82_1605 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | 0.918 |
| VC82_2557 | VC82_1939 | VC82_2557 | VC82_1939 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | NAD-binding malic protein; Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.446 |
| VC82_2557 | VC82_2847 | VC82_2557 | VC82_2847 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 2-oxoisovalerate dehydrogenase, E1 subunit; Pfam:pfam00676 Dehydrogenase E1 component. | 0.426 |
| VC82_2557 | VC82_2898 | VC82_2557 | VC82_2898 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Transketolase domain-containing protein; Pfam:pfam00676 Dehydrogenase E1 component. | 0.426 |
| VC82_2557 | VC82_563 | VC82_2557 | VC82_563 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pfam:pfam01515 Phosphate acetyl/butaryl transferase. | 0.929 |