| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VC82_1326 | VC82_1993 | VC82_1326 | VC82_1993 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | 0.961 |
| VC82_1326 | VC82_643 | VC82_1326 | VC82_643 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.991 |
| VC82_1326 | VC82_836 | VC82_1326 | VC82_836 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | FolC bifunctional protein; Pfam:pfam08245 Mur ligase middle domain. | 0.524 |
| VC82_1326 | folE | VC82_1326 | VC82_2691 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Pfam:pfam01227 GTP cyclohydrolase I. | 0.773 |
| VC82_1326 | folE-2 | VC82_1326 | VC82_662 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Pfam:pfam01227 GTP cyclohydrolase I. | 0.784 |
| VC82_1993 | VC82_1326 | VC82_1993 | VC82_1326 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.961 |
| VC82_1993 | VC82_643 | VC82_1993 | VC82_643 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
| VC82_1993 | VC82_836 | VC82_1993 | VC82_836 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | FolC bifunctional protein; Pfam:pfam08245 Mur ligase middle domain. | 0.633 |
| VC82_1993 | folE | VC82_1993 | VC82_2691 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | Pfam:pfam01227 GTP cyclohydrolase I. | 0.886 |
| VC82_1993 | folE-2 | VC82_1993 | VC82_662 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | Pfam:pfam01227 GTP cyclohydrolase I. | 0.817 |
| VC82_2230 | VC82_643 | VC82_2230 | VC82_643 | Anthranilate synthase subunit II; Pfam:pfam00117 Glutamine amidotransferase class-I. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.625 |
| VC82_642 | VC82_643 | VC82_642 | VC82_643 | DUF1599 family protein; Pfam:pfam07659 Domain of Unknown Function (DUF1599). | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.662 |
| VC82_642 | VC82_645 | VC82_642 | VC82_645 | DUF1599 family protein; Pfam:pfam07659 Domain of Unknown Function (DUF1599). | Pfam:pfam12412 Protein of unknown function (DUF3667). | 0.532 |
| VC82_642 | dacA | VC82_642 | VC82_644 | DUF1599 family protein; Pfam:pfam07659 Domain of Unknown Function (DUF1599). | Membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.573 |
| VC82_642 | tpiA | VC82_642 | VC82_640 | DUF1599 family protein; Pfam:pfam07659 Domain of Unknown Function (DUF1599). | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.799 |
| VC82_643 | VC82_1326 | VC82_643 | VC82_1326 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.991 |
| VC82_643 | VC82_1993 | VC82_643 | VC82_1993 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | 0.996 |
| VC82_643 | VC82_2230 | VC82_643 | VC82_2230 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase subunit II; Pfam:pfam00117 Glutamine amidotransferase class-I. | 0.625 |
| VC82_643 | VC82_642 | VC82_643 | VC82_642 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | DUF1599 family protein; Pfam:pfam07659 Domain of Unknown Function (DUF1599). | 0.662 |
| VC82_643 | VC82_645 | VC82_643 | VC82_645 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Pfam:pfam12412 Protein of unknown function (DUF3667). | 0.754 |