| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VC82_2046 | VC82_2061 | VC82_2046 | VC82_2061 | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.923 |
| VC82_2046 | VC82_2945 | VC82_2046 | VC82_2945 | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.933 |
| VC82_2046 | VC82_968 | VC82_2046 | VC82_968 | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | 0.900 |
| VC82_2046 | metK | VC82_2046 | VC82_2044 | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.917 |
| VC82_2061 | VC82_2046 | VC82_2061 | VC82_2046 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.923 |
| VC82_2061 | VC82_2945 | VC82_2061 | VC82_2945 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.918 |
| VC82_2061 | VC82_968 | VC82_2061 | VC82_968 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | 0.900 |
| VC82_2061 | metK | VC82_2061 | VC82_2044 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.924 |
| VC82_2061 | purH | VC82_2061 | VC82_969 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Pfam:pfam01808 AICARFT/IMPCHase bienzyme. | 0.900 |
| VC82_2945 | VC82_2046 | VC82_2945 | VC82_2046 | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.933 |
| VC82_2945 | VC82_2061 | VC82_2945 | VC82_2061 | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.918 |
| VC82_2945 | VC82_968 | VC82_2945 | VC82_968 | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | 0.900 |
| VC82_2945 | metK | VC82_2945 | VC82_2044 | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.918 |
| VC82_383 | VC82_968 | VC82_383 | VC82_968 | Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | 0.752 |
| VC82_967 | VC82_968 | VC82_967 | VC82_968 | Hypothetical protein. | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | 0.523 |
| VC82_968 | VC82_2046 | VC82_968 | VC82_2046 | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.900 |
| VC82_968 | VC82_2061 | VC82_968 | VC82_2061 | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.900 |
| VC82_968 | VC82_2945 | VC82_968 | VC82_2945 | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.900 |
| VC82_968 | VC82_383 | VC82_968 | VC82_383 | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.752 |
| VC82_968 | VC82_967 | VC82_968 | VC82_967 | Putative GAF sensor protein; Pfam:pfam01590 GAF domain. | Hypothetical protein. | 0.523 |