node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCZ85169.1 | SCZ85538.1 | NSMM_350033 | NSMM_400016 | Dihydroneopterin aldolase. | Aminotransferases class-IV. | 0.421 |
SCZ85169.1 | folC | NSMM_350033 | NSMM_340028 | Dihydroneopterin aldolase. | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.845 |
SCZ85169.1 | folK | NSMM_350033 | NSMM_1080008 | Dihydroneopterin aldolase. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.995 |
SCZ85169.1 | folP | NSMM_350033 | NSMM_370059 | Dihydroneopterin aldolase. | 7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.995 |
SCZ85169.1 | ilvE | NSMM_350033 | NSMM_400230 | Dihydroneopterin aldolase. | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.421 |
SCZ85538.1 | SCZ85169.1 | NSMM_400016 | NSMM_350033 | Aminotransferases class-IV. | Dihydroneopterin aldolase. | 0.421 |
SCZ85538.1 | folC | NSMM_400016 | NSMM_340028 | Aminotransferases class-IV. | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.616 |
SCZ85538.1 | folK | NSMM_400016 | NSMM_1080008 | Aminotransferases class-IV. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.573 |
SCZ85538.1 | folP | NSMM_400016 | NSMM_370059 | Aminotransferases class-IV. | 7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.728 |
SCZ85538.1 | ilvE | NSMM_400016 | NSMM_400230 | Aminotransferases class-IV. | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.551 |
SCZ85538.1 | mltG | NSMM_400016 | NSMM_150082 | Aminotransferases class-IV. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.601 |
SCZ85538.1 | trpE | NSMM_400016 | NSMM_400037 | Aminotransferases class-IV. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.745 |
folC | SCZ85169.1 | NSMM_340028 | NSMM_350033 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydroneopterin aldolase. | 0.845 |
folC | SCZ85538.1 | NSMM_340028 | NSMM_400016 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Aminotransferases class-IV. | 0.616 |
folC | folK | NSMM_340028 | NSMM_1080008 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.869 |
folC | folP | NSMM_340028 | NSMM_370059 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
folC | glyA | NSMM_340028 | NSMM_110011 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.951 |
folC | ilvE | NSMM_340028 | NSMM_400230 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.617 |
folC | mltG | NSMM_340028 | NSMM_150082 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.645 |
folC | trpE | NSMM_340028 | NSMM_400037 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.614 |