STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypDProtein required for maturation of hydrogenases; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the HypD family. (375 aa)    
Predicted Functional Partners:
hypE
Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
hypC
Hydrogenase expression/formation protein HypC.
 
 
 0.999
hypF
Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
  
 0.971
SCZ84440.1
Hypothetical protein; No homology to any previously reported sequences.
 
   
 0.522
SCZ84441.1
Nickel-dependent hydrogenase large subunit.
 
   
 0.433
purB
Adenylosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
      
 0.400
SCZ84972.1
Rubrerythrin.
      
 0.400
nirU
Copper-containing nitrite reductase; Belongs to the multicopper oxidase family.
      
 0.400
Your Current Organism:
Nitrosomonas mobilis
NCBI taxonomy Id: 51642
Other names: N. mobilis, Nitrosococcus mobilis, Nitrosomonas sp. Ms1, strain Nc 2
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