STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypFCarbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (764 aa)    
Predicted Functional Partners:
hypE
Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
hypC
Hydrogenase expression/formation protein HypC.
 
 
 0.972
hypD
Protein required for maturation of hydrogenases; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the HypD family.
 
  
 0.971
SCZ84440.1
Hypothetical protein; No homology to any previously reported sequences.
 
   
 0.539
SCZ84448.1
Hypothetical protein; No homology to any previously reported sequences.
    
  0.530
SCZ84441.1
Nickel-dependent hydrogenase large subunit.
 
   
 0.432
Your Current Organism:
Nitrosomonas mobilis
NCBI taxonomy Id: 51642
Other names: N. mobilis, Nitrosococcus mobilis, Nitrosomonas sp. Ms1, strain Nc 2
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.