| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU72_0232 | ADU72_0280 | ADU72_0232 | ADU72_0280 | Succinate-semialdehyde dehydrogenase [NAD(P)+]. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.825 |
| ADU72_0232 | ADU72_1296 | ADU72_0232 | ADU72_1296 | Succinate-semialdehyde dehydrogenase [NAD(P)+]. | Succinate-semialdehyde dehydrogenase [NAD(P)+]; Belongs to the aldehyde dehydrogenase family. | 0.902 |
| ADU72_0232 | ADU72_2161 | ADU72_0232 | ADU72_2161 | Succinate-semialdehyde dehydrogenase [NAD(P)+]. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.479 |
| ADU72_0280 | ADU72_0232 | ADU72_0280 | ADU72_0232 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Succinate-semialdehyde dehydrogenase [NAD(P)+]. | 0.825 |
| ADU72_0280 | ADU72_0624 | ADU72_0280 | ADU72_0624 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Biotin operon repressor; Biotin-protein ligase. | 0.952 |
| ADU72_0280 | ADU72_1296 | ADU72_0280 | ADU72_1296 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Succinate-semialdehyde dehydrogenase [NAD(P)+]; Belongs to the aldehyde dehydrogenase family. | 0.825 |
| ADU72_0280 | ADU72_1322 | ADU72_0280 | ADU72_1322 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.909 |
| ADU72_0280 | ADU72_1373 | ADU72_0280 | ADU72_1373 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.909 |
| ADU72_0280 | ADU72_1751 | ADU72_0280 | ADU72_1751 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. | 0.941 |
| ADU72_0280 | ADU72_2133 | ADU72_0280 | ADU72_2133 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.927 |
| ADU72_0280 | ADU72_2161 | ADU72_0280 | ADU72_2161 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.964 |
| ADU72_0280 | ADU72_2220 | ADU72_0280 | ADU72_2220 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.907 |
| ADU72_0280 | ldh | ADU72_0280 | ADU72_1500 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | 0.926 |
| ADU72_0624 | ADU72_0280 | ADU72_0624 | ADU72_0280 | Biotin operon repressor; Biotin-protein ligase. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.952 |
| ADU72_1296 | ADU72_0232 | ADU72_1296 | ADU72_0232 | Succinate-semialdehyde dehydrogenase [NAD(P)+]; Belongs to the aldehyde dehydrogenase family. | Succinate-semialdehyde dehydrogenase [NAD(P)+]. | 0.902 |
| ADU72_1296 | ADU72_0280 | ADU72_1296 | ADU72_0280 | Succinate-semialdehyde dehydrogenase [NAD(P)+]; Belongs to the aldehyde dehydrogenase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.825 |
| ADU72_1296 | ADU72_2161 | ADU72_1296 | ADU72_2161 | Succinate-semialdehyde dehydrogenase [NAD(P)+]; Belongs to the aldehyde dehydrogenase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.479 |
| ADU72_1322 | ADU72_0280 | ADU72_1322 | ADU72_0280 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.909 |
| ADU72_1322 | ADU72_1373 | ADU72_1322 | ADU72_1373 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.905 |
| ADU72_1322 | ADU72_1751 | ADU72_1322 | ADU72_1751 | Pyruvate oxidase; Belongs to the TPP enzyme family. | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. | 0.917 |