| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU72_0990 | ADU72_0991 | ADU72_0990 | ADU72_0991 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Integral membrane protein. | 0.654 |
| ADU72_0990 | guaA | ADU72_0990 | ADU72_0536 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.997 |
| ADU72_0990 | metG | ADU72_0990 | ADU72_0853 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.490 |
| ADU72_0990 | pheT | ADU72_0990 | ADU72_1952 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.588 |
| ADU72_0990 | ychF | ADU72_0990 | ADU72_0992 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GTP-binding and nucleic acid-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.702 |
| ADU72_0991 | ADU72_0990 | ADU72_0991 | ADU72_0990 | Integral membrane protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.654 |
| ADU72_0991 | ADU72_0993 | ADU72_0991 | ADU72_0993 | Integral membrane protein. | Protein involved in chromosome partitioning. | 0.567 |
| ADU72_0991 | ychF | ADU72_0991 | ADU72_0992 | Integral membrane protein. | GTP-binding and nucleic acid-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.774 |
| ADU72_0993 | ADU72_0991 | ADU72_0993 | ADU72_0991 | Protein involved in chromosome partitioning. | Integral membrane protein. | 0.567 |
| ADU72_0993 | ychF | ADU72_0993 | ADU72_0992 | Protein involved in chromosome partitioning. | GTP-binding and nucleic acid-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.806 |
| guaA | ADU72_0990 | ADU72_0536 | ADU72_0990 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.997 |
| guaA | lepA | ADU72_0536 | ADU72_0486 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.525 |
| guaA | lepA-2 | ADU72_0536 | ADU72_2198 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.525 |
| guaA | metG | ADU72_0536 | ADU72_0853 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.875 |
| guaA | pheT | ADU72_0536 | ADU72_1952 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.914 |
| guaA | pth | ADU72_0536 | ADU72_1501 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.699 |
| guaA | topA | ADU72_0536 | ADU72_2126 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.589 |
| guaA | ychF | ADU72_0536 | ADU72_0992 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | GTP-binding and nucleic acid-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.749 |
| lepA | guaA | ADU72_0486 | ADU72_0536 | Translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.525 |
| lepA | metG | ADU72_0486 | ADU72_0853 | Translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.457 |