STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU72_1328Dihydropteroate synthase. (379 aa)    
Predicted Functional Partners:
ADU72_1330
Dihydrofolate synthase at Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
 
 0.999
ADU72_1332
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
 
 0.999
ADU72_1333
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.999
folE
GTP cyclohydrolase I type 1.
  
 0.996
ADU72_1776
Dihydrofolate synthase at Folylpolyglutamate synthase.
 
 0.995
ADU72_1329
Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific).
 
  
 0.988
ADU72_0624
Biotin operon repressor; Biotin-protein ligase.
     
 0.634
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  
 0.541
folD
Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
   
 0.514
ADU72_1822
Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.504
Your Current Organism:
Pediococcus damnosus
NCBI taxonomy Id: 51663
Other names: ATCC 29358, CCUG 32251, CIP 102264, DSM 20331, JCM 5886, LMG 11484, LMG:11484, NCIMB 12010, P. damnosus, strain Be.1
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