STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (469 aa)    
Predicted Functional Partners:
SFV39031.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.960
SFV39127.1
Threonine dehydratase.
   
 
 0.905
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.904
SFV32314.1
O-acetylhomoserine sulfhydrylase.
     
 0.898
SFV32302.1
Homoserine dehydrogenase.
   
 
  0.886
thrB
Homoserine kinase; Belongs to the pseudomonas-type ThrB family.
    
  0.876
SFV29776.1
Cysteine synthase A.
  
 0.874
SFV32007.1
Cystathionine beta-lyase.
  
 0.867
SFV38015.1
Methionine adenosyltransferase; Belongs to the AdoMet synthase family.
 
 
 0.860
SFV37975.1
Cysteine synthase A.
  
 0.800
Your Current Organism:
Hyphomicrobium facile
NCBI taxonomy Id: 51670
Other names: ATCC 27485, H. facile, Hyphomicrobium facilis, IFAM H-526
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