STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFV29119.1Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (406 aa)    
Predicted Functional Partners:
SFV37653.1
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.988
SFV33541.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.980
SFV37548.1
2-oxoglutarate dehydrogenase E1 component.
   
 
 0.978
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.942
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.940
SFV29706.1
Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.929
SFV26728.1
Glutamate synthase (NADH) large subunit.
    
 0.927
argH
Argininosuccinate lyase.
     
 0.897
SFV27685.1
Aspartate aminotransferase.
   
 
 0.893
SFV29267.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.891
Your Current Organism:
Hyphomicrobium facile
NCBI taxonomy Id: 51670
Other names: ATCC 27485, H. facile, Hyphomicrobium facilis, IFAM H-526
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