node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFV29327.1 | SFV29339.1 | SAMN04488557_1224 | SAMN04488557_1227 | Acetolactate synthase, large subunit. | Acetolactate synthase, small subunit. | 0.999 |
SFV29327.1 | SFV38044.1 | SAMN04488557_1224 | SAMN04488557_3471 | Acetolactate synthase, large subunit. | Allosteric NADP-dependent malic enzyme. | 0.879 |
SFV29327.1 | SFV39106.1 | SAMN04488557_1224 | SAMN04488557_4131 | Acetolactate synthase, large subunit. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.882 |
SFV29327.1 | SFV39127.1 | SAMN04488557_1224 | SAMN04488557_4153 | Acetolactate synthase, large subunit. | Threonine dehydratase. | 0.972 |
SFV29327.1 | ilvC | SAMN04488557_1224 | SAMN04488557_1230 | Acetolactate synthase, large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.994 |
SFV29327.1 | ilvD | SAMN04488557_1224 | SAMN04488557_1830 | Acetolactate synthase, large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.981 |
SFV29327.1 | leuA | SAMN04488557_1224 | SAMN04488557_1235 | Acetolactate synthase, large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.921 |
SFV29327.1 | leuB | SAMN04488557_1224 | SAMN04488557_3316 | Acetolactate synthase, large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.968 |
SFV29327.1 | leuC | SAMN04488557_1224 | SAMN04488557_3367 | Acetolactate synthase, large subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.902 |
SFV29327.1 | leuD | SAMN04488557_1224 | SAMN04488557_3361 | Acetolactate synthase, large subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.915 |
SFV29339.1 | SFV29327.1 | SAMN04488557_1227 | SAMN04488557_1224 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit. | 0.999 |
SFV29339.1 | SFV38044.1 | SAMN04488557_1227 | SAMN04488557_3471 | Acetolactate synthase, small subunit. | Allosteric NADP-dependent malic enzyme. | 0.804 |
SFV29339.1 | SFV39106.1 | SAMN04488557_1227 | SAMN04488557_4131 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.975 |
SFV29339.1 | SFV39127.1 | SAMN04488557_1227 | SAMN04488557_4153 | Acetolactate synthase, small subunit. | Threonine dehydratase. | 0.991 |
SFV29339.1 | ilvC | SAMN04488557_1227 | SAMN04488557_1230 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
SFV29339.1 | ilvD | SAMN04488557_1227 | SAMN04488557_1830 | Acetolactate synthase, small subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.935 |
SFV29339.1 | leuA | SAMN04488557_1227 | SAMN04488557_1235 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.972 |
SFV29339.1 | leuB | SAMN04488557_1227 | SAMN04488557_3316 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.992 |
SFV29339.1 | leuC | SAMN04488557_1227 | SAMN04488557_3367 | Acetolactate synthase, small subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.920 |
SFV29339.1 | leuD | SAMN04488557_1227 | SAMN04488557_3361 | Acetolactate synthase, small subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.938 |