STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFV36674.1Membrane protease subunit HflK; HflC and HflK could encode or regulate a protease. (399 aa)    
Predicted Functional Partners:
SFV36673.1
Protease FtsH subunit HflC; HflC and HflK could regulate a protease.
 
 
 0.999
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
 0.996
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.840
SFV36672.1
Hypothetical protein.
       0.777
SFV38231.1
Membrane associated serine protease, rhomboid family.
   
 0.755
SFV39020.1
Membrane associated serine protease, rhomboid family.
   
 0.755
yidC
Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
 
 0.625
SFV36671.1
Serine protease Do; Belongs to the peptidase S1C family.
  
 
 0.583
SFV38101.1
Regulator of protease activity HflC, stomatin/prohibitin superfamily.
  
   
 0.553
SFV36675.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.539
Your Current Organism:
Hyphomicrobium facile
NCBI taxonomy Id: 51670
Other names: ATCC 27485, H. facile, Hyphomicrobium facilis, IFAM H-526
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