Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SFV37523.1Magnesium chelatase family protein. (509 aa)    
Predicted Functional Partners:
SFV37444.1
comF family protein; Manually curated.
 
  
 0.808
SFV28333.1
DNA processing protein.
 
 
 0.793
SFV37521.1
KTSC domain-containing protein.
       0.718
SFV33535.1
Competence protein ComEC.
 
  
 0.692
ruvC
Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.691
SFV37267.1
Flagellar basal-body rod protein FlgF; Belongs to the flagella basal body rod proteins family.
   
   0.655
SFV28443.1
Response regulator receiver domain-containing protein.
  
  
 0.530
gshB
Glutathione synthase; Belongs to the prokaryotic GSH synthase family.
       0.515
nnrD
NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...]
 
     0.501
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
 
     0.467
Your Current Organism:
Hyphomicrobium facile
NCBI taxonomy Id: 51670
Other names: ATCC 27485, H. facile, Hyphomicrobium facilis, IFAM H-526
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