node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFV26128.1 | SFV26225.1 | SAMN04488557_0339 | SAMN04488557_0383 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Dihydrolipoamide dehydrogenase. | 0.932 |
SFV26128.1 | SFV27426.1 | SAMN04488557_0339 | SAMN04488557_0757 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.902 |
SFV26128.1 | SFV37679.1 | SAMN04488557_0339 | SAMN04488557_3285 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinate dehydrogenase subunit C. | 0.997 |
SFV26128.1 | SFV37681.1 | SAMN04488557_0339 | SAMN04488557_3286 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinate dehydrogenase / fumarate reductase membrane anchor subunit. | 0.975 |
SFV26128.1 | SFV37687.1 | SAMN04488557_0339 | SAMN04488557_3289 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.997 |
SFV26128.1 | fumC | SAMN04488557_0339 | SAMN04488557_2667 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.923 |
SFV26128.1 | nuoI | SAMN04488557_0339 | SAMN04488557_2059 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.889 |
SFV26128.1 | sucC-2 | SAMN04488557_0339 | SAMN04488557_3221 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.769 |
SFV26128.1 | sucD-2 | SAMN04488557_0339 | SAMN04488557_3220 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.763 |
SFV26225.1 | SFV26128.1 | SAMN04488557_0383 | SAMN04488557_0339 | Dihydrolipoamide dehydrogenase. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.932 |
SFV26225.1 | SFV27426.1 | SAMN04488557_0383 | SAMN04488557_0757 | Dihydrolipoamide dehydrogenase. | Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.547 |
SFV26225.1 | SFV37679.1 | SAMN04488557_0383 | SAMN04488557_3285 | Dihydrolipoamide dehydrogenase. | Succinate dehydrogenase subunit C. | 0.852 |
SFV26225.1 | SFV37681.1 | SAMN04488557_0383 | SAMN04488557_3286 | Dihydrolipoamide dehydrogenase. | Succinate dehydrogenase / fumarate reductase membrane anchor subunit. | 0.762 |
SFV26225.1 | SFV37683.1 | SAMN04488557_0383 | SAMN04488557_3287 | Dihydrolipoamide dehydrogenase. | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.932 |
SFV26225.1 | SFV37687.1 | SAMN04488557_0383 | SAMN04488557_3289 | Dihydrolipoamide dehydrogenase. | Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.978 |
SFV26225.1 | fumC | SAMN04488557_0383 | SAMN04488557_2667 | Dihydrolipoamide dehydrogenase. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.787 |
SFV26225.1 | nuoI | SAMN04488557_0383 | SAMN04488557_2059 | Dihydrolipoamide dehydrogenase. | NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.906 |
SFV26225.1 | sucC-2 | SAMN04488557_0383 | SAMN04488557_3221 | Dihydrolipoamide dehydrogenase. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.949 |
SFV26225.1 | sucD-2 | SAMN04488557_0383 | SAMN04488557_3220 | Dihydrolipoamide dehydrogenase. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.936 |
SFV27426.1 | SFV26128.1 | SAMN04488557_0757 | SAMN04488557_0339 | Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.902 |