STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ctha_0409Peptidylprolyl isomerase; PFAM: HEAT domain containing protein; peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sru:SRU_2431 peptidyl-prolyl cis-trans isomerase, cyclophilin-type domain protein. (694 aa)    
Predicted Functional Partners:
Ctha_0766
WD-40 repeat protein; PFAM: heat shock protein DnaJ domain protein; WD-40 repeat protein; KEGG: ana:all0438 serine/threonine kinase with WD-40 repeat.
 
 0.972
efp
Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
 0.968
Ctha_0310
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: mxa:MXAN_4081 putative ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family.
 
 0.955
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.924
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 
 0.892
Ctha_0061
PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: fjo:Fjoh_2374 chaperone DnaJ domain protein.
  
 
 0.871
Ctha_2590
PFAM: heat shock protein DnaJ domain protein; KEGG: abu:Abu_1294 co-chaperone and heat shock protein DnaJ.
  
 
 0.871
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.798
rpsQ
Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.784
rplX
Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.782
Your Current Organism:
Chloroherpeton thalassium
NCBI taxonomy Id: 517418
Other names: C. thalassium ATCC 35110, Chloroherpeton thalassium ATCC 35110, Chloroherpeton thalassium str. ATCC 35110, Chloroherpeton thalassium strain ATCC 35110
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