node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ctha_0486 | Ctha_2613 | Ctha_0486 | Ctha_2613 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pvi:Cvib_1256 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.900 |
Ctha_0486 | queC | Ctha_0486 | Ctha_1495 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.827 |
Ctha_0486 | queE | Ctha_0486 | Ctha_1550 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.981 |
Ctha_0486 | queF | Ctha_0486 | Ctha_2633 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.782 |
Ctha_0716 | queC | Ctha_0716 | Ctha_1495 | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; thiamineS protein; MoeZ/MoeB domain protein; KEGG: cau:Caur_3492 UBA/ThiF-type NAD/FAD binding protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.427 |
Ctha_2613 | Ctha_0486 | Ctha_2613 | Ctha_0486 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pvi:Cvib_1256 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.900 |
Ctha_2613 | queC | Ctha_2613 | Ctha_1495 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pvi:Cvib_1256 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.857 |
Ctha_2613 | queE | Ctha_2613 | Ctha_1550 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pvi:Cvib_1256 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.985 |
Ctha_2613 | queF | Ctha_2613 | Ctha_2633 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pvi:Cvib_1256 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.796 |
queC | Ctha_0486 | Ctha_1495 | Ctha_0486 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.827 |
queC | Ctha_0716 | Ctha_1495 | Ctha_0716 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; thiamineS protein; MoeZ/MoeB domain protein; KEGG: cau:Caur_3492 UBA/ThiF-type NAD/FAD binding protein. | 0.427 |
queC | Ctha_2613 | Ctha_1495 | Ctha_2613 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pvi:Cvib_1256 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.857 |
queC | queE | Ctha_1495 | Ctha_1550 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.994 |
queC | queF | Ctha_1495 | Ctha_2633 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.988 |
queE | Ctha_0486 | Ctha_1550 | Ctha_0486 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.981 |
queE | Ctha_2613 | Ctha_1550 | Ctha_2613 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pvi:Cvib_1256 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.985 |
queE | queC | Ctha_1550 | Ctha_1495 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.994 |
queE | queF | Ctha_1550 | Ctha_2633 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.892 |
queF | Ctha_0486 | Ctha_2633 | Ctha_0486 | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.782 |
queF | Ctha_2613 | Ctha_2633 | Ctha_2613 | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pvi:Cvib_1256 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.796 |