node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ctha_0303 | ruvC | Ctha_0303 | Ctha_1787 | KEGG: cph:Cpha266_0558 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.461 |
Ctha_1786 | Ctha_1788 | Ctha_1786 | Ctha_1788 | PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein. | PFAM: TspO/MBR family protein; KEGG: cph:Cpha266_0544 TspO and MBR like proteins. | 0.429 |
Ctha_1786 | Ctha_1915 | Ctha_1786 | Ctha_1915 | PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein. | KEGG: cte:CT0840 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | 0.401 |
Ctha_1786 | pheA | Ctha_1786 | Ctha_1785 | PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cph:Cpha266_0537 prephenate dehydratase. | 0.548 |
Ctha_1786 | ruvC | Ctha_1786 | Ctha_1787 | PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.831 |
Ctha_1788 | Ctha_1786 | Ctha_1788 | Ctha_1786 | PFAM: TspO/MBR family protein; KEGG: cph:Cpha266_0544 TspO and MBR like proteins. | PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein. | 0.429 |
Ctha_1788 | ruvC | Ctha_1788 | Ctha_1787 | PFAM: TspO/MBR family protein; KEGG: cph:Cpha266_0544 TspO and MBR like proteins. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.486 |
Ctha_1915 | Ctha_1786 | Ctha_1915 | Ctha_1786 | KEGG: cte:CT0840 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein. | 0.401 |
Ctha_1915 | polA | Ctha_1915 | Ctha_2636 | KEGG: cte:CT0840 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.537 |
Ctha_1915 | ruvC | Ctha_1915 | Ctha_1787 | KEGG: cte:CT0840 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.504 |
Ctha_2263 | polA | Ctha_2263 | Ctha_2636 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cph:Cpha266_0687 single-stranded-DNA-specific exonuclease RecJ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.490 |
Ctha_2263 | ruvC | Ctha_2263 | Ctha_1787 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cph:Cpha266_0687 single-stranded-DNA-specific exonuclease RecJ. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.483 |
pheA | Ctha_1786 | Ctha_1785 | Ctha_1786 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cph:Cpha266_0537 prephenate dehydratase. | PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein. | 0.548 |
pheA | ruvC | Ctha_1785 | Ctha_1787 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cph:Cpha266_0537 prephenate dehydratase. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.465 |
polA | Ctha_1915 | Ctha_2636 | Ctha_1915 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | KEGG: cte:CT0840 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | 0.537 |
polA | Ctha_2263 | Ctha_2636 | Ctha_2263 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cph:Cpha266_0687 single-stranded-DNA-specific exonuclease RecJ. | 0.490 |
polA | recX | Ctha_2636 | Ctha_0526 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.465 |
polA | ruvA | Ctha_2636 | Ctha_0592 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.456 |
polA | ruvB | Ctha_2636 | Ctha_0003 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.587 |
polA | ruvC | Ctha_2636 | Ctha_1787 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.512 |