STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFD01482.1Citrate synthase. (264 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.983
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.972
SFC67699.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.970
SFC65737.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.957
SFC23094.1
Glutamate synthase (NADPH) large subunit.
    
 0.942
SFC42799.1
2-methylcitrate dehydratase PrpD.
 
 
 0.934
SFC38067.1
Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.933
SFD01502.1
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
  0.904
SFC56883.1
Biotin-requiring enzyme.
  
 0.897
SFC65768.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.895
Your Current Organism:
Pseudooceanicola nitratireducens
NCBI taxonomy Id: 517719
Other names: CGMCC 1.7292, DSM 29619, LMG 24663, LMG:24663, Oceanicola nitratireducens, Oceanicola nitratireducens Zheng et al. 2010, Oceanicola sp. JLT1210, P. nitratireducens, Pseudooceanicola nitratireducens (Zheng et al. 2010) Lai et al. 2015, strain JLT1210
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