STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (290 aa)    
Predicted Functional Partners:
thrC
Threonine synthase; KEGG: cac:CAC0999 4.8e-116 thrC; threonine synthase K01733; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
EEC91391.1
KEGG: ldb:Ldb1350 4.0e-57 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87.
 
 0.998
EEC91390.1
Amino acid kinase family; KEGG: cno:NT01CX_0187 3.6e-111 aspartate kinase, putative K00928; Belongs to the aspartokinase family.
 
 0.952
EEC91394.1
ACT domain protein; KEGG: ctc:CTC00116 3.2e-32 chorismate mutase K06209; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0735 family.
 
  
  0.912
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: gka:GK0265 7.6e-102 phosphoribosylaminoimidazole synthetase K01933; Psort location: Cytoplasmic, score: 8.87.
 
    
 0.911
EEC90417.1
Putative L-serine ammonia-lyase; KEGG: pgi:PG0084 6.2e-84 sda; L-serine dehydratase, iron-sulfur-dependent, single chain form K01752; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.887
cysE
KEGG: dar:Daro_1947 2.4e-50 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.98.
     
 0.876
EEC89838.1
Aminotransferase, class I/II; KEGG: blo:BL1776 5.9e-111 probable aminotransferase K00842; Psort location: Cytoplasmic, score: 8.87.
 
  
  0.865
ilvE
Branched-chain-amino-acid transaminase; KEGG: sab:SAB0505 8.9e-108 branched-chain amino acid aminotransferase K00826; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.859
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
 0.833
Your Current Organism:
Holdemanella biformis
NCBI taxonomy Id: 518637
Other names: Eubacterium biforme DSM 3989, H. biformis DSM 3989, Holdemanella biformis DSM 3989
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.