STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEC90862.1KEGG: rru:Rru_A1450 1.6e-07 transcriptional regulator, ArsR family. (92 aa)    
Predicted Functional Partners:
EEC90861.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.973
EEC90863.1
Macro domain protein; KEGG: bur:Bcep18194_A6181 1.6e-37 Appr-1-p processing enzyme family K00985; Psort location: Cytoplasmic, score: 8.87.
  
    0.524
EEC90864.1
Hypothetical protein.
       0.515
cobB
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 
  0.506
EEC89942.1
Copper-exporting ATPase; KEGG: cpe:CPE0555 2.3e-206 probable copper-transporting ATPase K01533; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.476
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.87.
     
 0.469
EEC91279.1
Glycosyltransferase, group 2 family protein; KEGG: gbe:GbCGDNIH1_2152 4.6e-88 glycosyltransferase K00754.
     
 0.461
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
  0.454
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
  0.446
cysK
Cysteine synthase A; KEGG: bth:BT3080 4.8e-109 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.444
Your Current Organism:
Holdemanella biformis
NCBI taxonomy Id: 518637
Other names: Eubacterium biforme DSM 3989, H. biformis DSM 3989, Holdemanella biformis DSM 3989
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.