STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEC90683.1DNA topoisomerase; KEGG: efa:EF2312 2.7e-113 topB-2; DNA topoisomerase III K03169; Psort location: Cytoplasmic, score: 8.87. (494 aa)    
Predicted Functional Partners:
EEC90669.1
Topoisomerase DNA-binding C4 zinc finger domain protein; KEGG: efa:EF2312 9.9e-44 topB-2; DNA topoisomerase III K03169; Psort location: Cytoplasmic, score: 8.87.
     0.978
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.932
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.87.
  
   0.925
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.922
asnS
asparagine--tRNA ligase; KEGG: bar:GBAA4802 1.2e-151 asnS; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 10.00.
  
 
 0.829
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.791
EEC90682.1
Resolvase, N-terminal domain protein; Psort location: Cytoplasmic, score: 8.87.
     
 0.783
EEC90684.1
Hypothetical protein; KEGG: mpe:MYPE6470 6.6e-05 parC; DNA topoisomerase IV subunit A K02621.
 
     0.775
EEC89925.1
SNF2 family N-terminal domain protein; KEGG: lwe:lwe1660 1.2e-110 DNA/RNA helicase protein K01529; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.775
EEC90681.1
Hypothetical protein.
       0.773
Your Current Organism:
Holdemanella biformis
NCBI taxonomy Id: 518637
Other names: Eubacterium biforme DSM 3989, H. biformis DSM 3989, Holdemanella biformis DSM 3989
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