STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerCPhage integrase SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (291 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.856
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.87.
    
  0.839
trmFO
tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
  
    0.822
dprA
DNA protecting protein DprA; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.710
EEC91034.1
FtsK/SpoIIIE family protein; KEGG: reh:H16_A1582 1.0e-108 DNA segregation ATPase FtsK/SpoIIIE related protein; Psort location: CytoplasmicMembrane, score: 9.97; Belongs to the FtsK/SpoIIIE/SftA family.
 
   
 0.588
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.581
ylqF
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
     
 0.580
rpsB
Ribosomal protein S2; Psort location: Cytoplasmic, score: 8.87; Belongs to the universal ribosomal protein uS2 family.
       0.543
lepB-2
Signal peptidase I; KEGG: bsu:BG10515 2.5e-25 sipS; type I signal peptidase K03100; Belongs to the peptidase S26 family.
     
 0.536
tsf
Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
     
 0.517
Your Current Organism:
Holdemanella biformis
NCBI taxonomy Id: 518637
Other names: Eubacterium biforme DSM 3989, H. biformis DSM 3989, Holdemanella biformis DSM 3989
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