STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrEYjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (498 aa)    
Predicted Functional Partners:
EEC90181.1
Hydrolase, NUDIX family; KEGG: bha:BH1524 6.0e-31 ADP-ribose pyrophosphatase, putative K01515; Psort location: Cytoplasmic, score: 8.87.
  
 0.996
EEC90060.1
Hydrolase, NUDIX family; KEGG: bfs:BF4099 3.1e-25 putative NUDIX/MutT-family protein K01515.
 
 0.996
EEC90955.1
DEAD/DEAH box helicase; KEGG: hac:Hac_1370 6.9e-69 deaD; ATP-dependent RNA helicase; Psort location: Cytoplasmic, score: 8.87; Belongs to the DEAD box helicase family.
  
 0.994
EEC90262.1
DEAD/DEAH box helicase; KEGG: sab:SAB1430c 1.9e-80 probable ATP-dependent RNA helicase K01529; Psort location: Cytoplasmic, score: 8.87.
  
 0.994
EEC89708.1
Hydrolase, P-loop family; KEGG: cjk:jk1734 1.9e-09 alr; hypothetical protein K01775; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.802
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.764
EEC91084.1
RNA methyltransferase, TrmH family; KEGG: gka:GK2709 5.4e-46 rRNA methylase K03437; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.679
EEC90001.1
KEGG: chy:CHY_2335 4.0e-18 RNA methyltransferase, TrmH family, group 3 K03218; Psort location: Cytoplasmic, score: 8.87; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
   
 
 0.679
EEC89220.1
KEGG: cch:Cag_1731 2.4e-07 RNA methyltransferase TrmH, group 3 K03218.
   
 
 0.679
EEC89221.1
RNA methyltransferase, TrmH family; KEGG: bha:BH0113 3.9e-43 tRNA/rRNA methyltransferase K03218; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
   
 
 0.679
Your Current Organism:
Holdemanella biformis
NCBI taxonomy Id: 518637
Other names: Eubacterium biforme DSM 3989, H. biformis DSM 3989, Holdemanella biformis DSM 3989
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.