Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Rmar_1663Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: aba:Acid345_1428 propionyl-CoA carboxylase. (560 aa)    
Predicted Functional Partners:
Rmar_0675
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.993
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 0.821
Rmar_2658
PFAM: pyruvate carboxyltransferase; KEGG: mxa:MXAN_3753 hydroxymethylglutaryl-CoA lyase.
 
 
 0.808
Rmar_1436
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: nar:Saro_3419 acyl-CoA dehydrogenase domain- containing protein.
 
 
 0.800
Rmar_1469
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: pmy:Pmen_2590 short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.750
Rmar_1707
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: bsu:BSU32840 hypothetical protein.
  
 
 0.750
Rmar_1556
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: Aldehyde Dehydrogenase; MaoC domain protein dehydratase; KEGG: dsh:Dshi_3827 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
  
 
 0.658
Rmar_0042
2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; KEGG: bba:Bd2500 2-methylcitrate dehydratase.
  
    0.639
icmF
Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
  
 0.620
Rmar_2207
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: dal:Dalk_2466 acyl-CoA dehydrogenase domain protein.
 
 
 0.616
Your Current Organism:
Rhodothermus marinus
NCBI taxonomy Id: 518766
Other names: R. marinus DSM 4252, Rhodothermus marinus DSM 4252, Rhodothermus marinus str. DSM 4252, Rhodothermus marinus strain DSM 4252
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