STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rmar_1663Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: aba:Acid345_1428 propionyl-CoA carboxylase. (560 aa)    
Predicted Functional Partners:
Rmar_0675
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.996
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 0.898
Rmar_2658
PFAM: pyruvate carboxyltransferase; KEGG: mxa:MXAN_3753 hydroxymethylglutaryl-CoA lyase.
 
 
 0.782
Rmar_1436
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: nar:Saro_3419 acyl-CoA dehydrogenase domain- containing protein.
 
  
 0.759
Rmar_1469
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: pmy:Pmen_2590 short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.756
Rmar_1707
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: bsu:BSU32840 hypothetical protein.
  
 
 0.756
icmF
Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
  
 0.611
Rmar_1556
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: Aldehyde Dehydrogenase; MaoC domain protein dehydratase; KEGG: dsh:Dshi_3827 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
  
 
 0.606
Rmar_0991
PFAM: dehydrogenase E1 component; Transketolase domain protein; Transketolase central region; KEGG: sus:Acid_3687 dehydrogenase, E1 component.
  
  
 0.604
Rmar_1486
PFAM: dehydrogenase E1 component; Transketolase domain protein; Transketolase central region; KEGG: jan:Jann_3081 dehydrogenase, E1 component.
  
  
 0.604
Your Current Organism:
Rhodothermus marinus
NCBI taxonomy Id: 518766
Other names: R. marinus DSM 4252, Rhodothermus marinus DSM 4252, Rhodothermus marinus str. DSM 4252, Rhodothermus marinus strain DSM 4252
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.