STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (237 aa)    
Predicted Functional Partners:
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
 0.999
sat
ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.992
cysI
Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 0.980
KYG34769.1
Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
 
 
 0.965
KYG34823.1
Sulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.934
KYG34821.1
Sulfate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.926
cysA
Sulfate ABC transporter; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
 
 0.923
KYG34822.1
Sulfate ABC transporter permease; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
  
 
 0.915
KYG32136.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.910
KYG25983.1
Heat-shock protein HtpX; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.812
Your Current Organism:
Bacillus trypoxylicola
NCBI taxonomy Id: 519424
Other names: B. trypoxylicola, Bacillus trypoxylicola Aizawa et al. 2010, KCTC 13244, NBRC 102646, strain SU1
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