Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Smon_0139KEGG: bcr:BCAH187_A2111 tagatose 1,6-diphosphate aldolase; TIGRFAM: tagatose 1,6-diphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase. (324 aa)    
Predicted Functional Partners:
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.909
Smon_0116
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: bcz:pE33L466_0341 keto-hydroxyglutarate- aldolase/keto-deoxy-phosphogluconate aldolase.
     
  0.800
Smon_0800
PFAM: Aldehyde Dehydrogenase; KEGG: bha:BH2237 NADP-dependent glyceraldehyde-3- phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
  0.800
Smon_0147
PFAM: sugar isomerase (SIS); KEGG: vfi:VF_A1004 tagatose-6-phosphate ketose/aldose isomerase.
 
     0.764
Smon_1400
PFAM: PTS system Galactitol-specific IIC component; KEGG: phosphotransferase system enzyme subunit; K02775 PTS system, galactitol-specific IIC component.
 
     0.462
Smon_0198
PFAM: phosphotransferase system lactose/cellobiose- specific IIB subunit; KEGG: ppr:PBPRB2008 PTS system cellobiose-specific IIB component.
  
  
 0.418
Smon_0199
PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
  
  
 0.415
Smon_0559
KEGG: dds:Ddes_1446 ribose 5-phosphate isomerase B; TIGRFAM: ribose 5-phosphate isomerase B; sugar- phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase.
  
  
 0.411
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.