Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Smon_0295Cysteine desulfurase; PFAM: aminotransferase class V; KEGG: cbc:CbuK_1045 cysteine desulfhydrase. (373 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.966
Smon_0721
Hypothetical protein; Belongs to the sulfur carrier protein TusA family.
   
 0.965
Smon_1070
TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: pin:Ping_1504 SUF system FeS assembly protein, NifU family protein.
 
 0.965
Smon_1475
Cysteine desulfurase; PFAM: aminotransferase class V; KEGG: lip:LI0265 cysteine sulfinate desulfinase/cysteine desulfurase.
  
  
 
0.920
Smon_0718
PFAM: SirA family protein; KEGG: sgl:SG1742 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
   
 
 0.673
Smon_0293
Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
   
   0.654
Smon_0294
PFAM: Domain of unknown function DUF1957; glycoside hydrolase family 57; KEGG: ank:AnaeK_1135 domain of unknown function DUF1957; Belongs to the glycosyl hydrolase 57 family.
       0.653
Smon_0300
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cco:CCC13826_1933 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
  
 0.631
Smon_0292
TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: wbr:WGLp195 hypothetical protein.
  
    0.630
Smon_1139
Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
0.610
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
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