Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1465 aa)    
Predicted Functional Partners:
Smon_0578
KEGG: ecn:Ecaj_0815 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain.
   
 0.936
Smon_0366
PFAM: DNA polymerase III delta; KEGG: conserved hypothetical protein.
    
 0.929
Smon_1474
KEGG: bcr:BCAH187_A4730 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; SMART: phosphoesterase PHP domain protein.
    
0.929
Smon_0637
KEGG: pub:SAR11_1000 DNA polymerase III.
  
 0.923
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.923
Smon_0754
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: abu:Abu_1113 hypothetical protein.
    
 0.915
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.797
Smon_0331
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: adsl; adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
       0.786
Smon_0329
KEGG: vco:VC0395_A0117 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.748
Smon_0712
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: bha:BH1327 hypothetical protein.
  
     0.748
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.