Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (310 aa)    
Predicted Functional Partners:
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.
  
    0.853
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
       0.819
Smon_0630
TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; KEGG: ppd:Ppro_1802 SpoIID/LytB domain-containing protein.
       0.818
Smon_0628
TIGRFAM: sporulation integral membrane protein YtvI; PFAM: protein of unknown function UPF0118; KEGG: bha:BH0463 hypothetical protein.
       0.663
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.610
rpmF
TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: mno:Mnod_5920 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
    0.600
Smon_0597
TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: cco:CCC13826_0048 succinate dehydrogenase, iron-sulfur protein subunit.
  
   
 0.592
Smon_0567
TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: bsu:BSU00390 hypothetical protein.
      0.572
Smon_0743
Shikimate 5-dehydrogenase-like protein; KEGG: pub:SAR11_0341 shikimate 5-dehydrogenase.
  
    0.544
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
    0.523
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
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