Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Smon_0672PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: esa:ESA_03308 ribonucleoside hydrolase RihC. (306 aa)    
Predicted Functional Partners:
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.938
Smon_0673
TIGRFAM: anaerobic c4-dicarboxylate antiporter, DcuC family; PFAM: C4-dicarboxylate anaerobic carrier; Na+/H+ antiporter NhaC; Citrate transporter; TRAP C4- dicarboxylate transport system permease DctM subunit; KEGG: dno:DNO_1353 C4-dicarboxylate anaerobic carrier, DcuC family protein.
 
     0.900
Smon_0670
PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_4885 acetyltransferase.
       0.797
Smon_0511
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
 0.620
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.602
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.602
Smon_0669
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: msu:MS0284 PurR protein.
     
 0.588
Smon_0678
PFAM: cobalt transport protein; KEGG: hha:Hhal_0380 cobalt transport protein.
       0.539
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 
  0.509
Smon_0677
TIGRFAM: conserved hypothetical protein.
       0.504
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
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