Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Smon_0812PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: NADH oxidase lateral transfer candidate. (444 aa)    
Predicted Functional Partners:
Smon_0811
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: bsu:BSU28500 thioredoxin; Belongs to the thioredoxin family.
     
 0.772
Smon_0813
Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
    0.702
Smon_0814
PFAM: protein of unknown function DUF606; KEGG: dds:Ddes_0202 protein of unknown function DUF606.
       0.683
Smon_0815
PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: nis:NIS_0066 recombination factor protein RarA.
       0.677
Smon_0816
KEGG: gur:Gura_3250 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77.
       0.664
Smon_1215
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1418 2-oxoglutarate dehydrogenase E3 component.
  
 
 0.612
Smon_0443
PFAM: beta-lactamase domain protein; KEGG: bha:BH2820 hypothetical protein.
   
 0.586
Smon_0818
TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN; KEGG: pin:Ping_1819 putative ribonuclease BN.
  
  
 0.581
Smon_0821
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
       0.556
Smon_0817
PFAM: protein of unknown function DUF195; KEGG: cps:CPS_3589 hypothetical protein.
       0.548
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
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