Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Smon_0916KEGG: hypothetical protein. (420 aa)    
Predicted Functional Partners:
smc
SMC domain protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.791
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.785
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.781
Smon_0920
Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: bsu:BSU32810 hypothetical protein; Belongs to the ArsC family.
       0.776
Smon_0918
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: dps:DP2271 deoxycytidylate deaminase.
       0.775
Smon_0922
PFAM: protein of unknown function DUF187; KEGG: bsu:BSU18280 hypothetical protein.
       0.775
Smon_0923
PFAM: O-methyltransferase family 3; KEGG: bcb:BCB4264_A4503 O-methyltransferase family protein.
       0.768
Smon_0958
PFAM: GCN5-related N-acetyltransferase; KEGG: wsu:WS0070 hypothetical protein.
 
    0.758
Smon_1129
TIGRFAM: conserved hypothetical protein; KEGG: bcr:BCAH187_A0963 putative ABC transporter, permease protein.
  
     0.754
Smon_0550
Pseudouridylate synthase-like protein; KEGG: nis:NIS_1108 tRNA pseudouridine synthase A; Belongs to the tRNA pseudouridine synthase TruA family.
 
     0.743
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
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