Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Smon_0949PFAM: Uracil-DNA glycosylase superfamily; KEGG: uracil-DNA glycosylase; K03648 uracil-DNA glycosylase; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (537 aa)    
Predicted Functional Partners:
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
     
 0.823
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.818
asnA
Aspartate/ammonia ligase; KEGG: bcy:Bcer98_1427 asparagine synthetase AsnA; TIGRFAM: aspartate/ammonia ligase; PFAM: aspartate--ammonia ligase.
       0.814
Smon_0578
KEGG: ecn:Ecaj_0815 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain.
   
 
 0.790
rnj
Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.760
Smon_0785
KEGG: bcb:BCB4264_A3839 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
  
 0.757
Smon_0952
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: bha:BH0467 hypothetical protein.
       0.746
Smon_0953
KEGG: bcy:Bcer98_1037 TrkH family potassium uptake protein; TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter.
       0.746
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
       0.739
Smon_0954
PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cha:CHAB381_1752 foldase protein PrsA.
 
     0.663
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
Server load: low (26%) [HD]