Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (309 aa)    
Predicted Functional Partners:
Smon_0300
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cco:CCC13826_1933 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 0.997
Smon_1217
PFAM: Transketolase domain protein; Transketolase central region; KEGG: bha:BH0777 acetoin dehydrogenase (TPP- dependent) beta chain.
  
 0.982
Smon_0413
KEGG: esa:ESA_02086 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.979
Smon_0549
PFAM: aminotransferase class I and II; KEGG: ftn:FTN_0410 aspartate aminotransferase.
  
 0.958
Smon_1058
KEGG: bcy:Bcer98_0431 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C- acetyltransferase glycine radical.
  
 
 0.936
Smon_1218
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; KEGG: bha:BH0776 acetoin dehydrogenase (TPP- dependent) alpha chain.
  
 
 0.935
Smon_1448
PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: hha:Hhal_0052 AMP-dependent synthetase and ligase.
  
 
 0.935
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: bsu:BSU31350 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.919
Smon_0800
PFAM: Aldehyde Dehydrogenase; KEGG: bha:BH2237 NADP-dependent glyceraldehyde-3- phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.904
atpA-2
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
  
 0.890
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
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