Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Smon_1292KEGG: hit:NTHI0932 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (354 aa)    
Predicted Functional Partners:
Smon_1291
KEGG: tcx:Tcr_1719 hydroxymethylglutaryl-coenzyme A synthase; TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain protein; Hydroxymethylglutaryl-coenzyme A synthase domain.
  
 0.999
Smon_0300
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cco:CCC13826_1933 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.979
Smon_1052
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: eta:ETA_15810 aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.963
Smon_1290
TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; KEGG: mxa:MXAN_5020 hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.957
Smon_0076
TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; KEGG: abu:Abu_0493 phosphate acetyltransferase.
  
 
 0.939
Smon_1216
PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: bha:BH0778 branched-chain alpha-keto acid dehydrogenase subunit E2.
  
 
 0.930
Smon_1058
KEGG: bcy:Bcer98_0431 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C- acetyltransferase glycine radical.
     
 0.919
Smon_1215
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1418 2-oxoglutarate dehydrogenase E3 component.
  
 0.805
Smon_1288
PFAM: aldo/keto reductase; KEGG: bcy:Bcer98_2796 2,5-didehydrogluconate reductase.
  
 
 0.796
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
  0.753
Your Current Organism:
Streptobacillus moniliformis
NCBI taxonomy Id: 519441
Other names: S. moniliformis DSM 12112, Streptobacillus moniliformis ATCC 14647, Streptobacillus moniliformis DSM 12112, Streptobacillus moniliformis str. DSM 12112, Streptobacillus moniliformis strain DSM 12112
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