STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Huta_0228PFAM: tRNA methyltransferase complex GCD14 subunit; O-methyltransferase family 3; KEGG: nph:NP0356A methyltransferase. (243 aa)    
Predicted Functional Partners:
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
    0.885
nac
alpha-NAC related protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.820
rps8e
TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8E; KEGG: hma:rrnAC1511 30S ribosomal protein S8e.
  
    0.765
rpl30
TIGRFAM: ribosomal protein L30P; PFAM: ribosomal protein L30; KEGG: nph:NP4896A 50S ribosomal protein L30P.
   
   0.753
tmcA
Protein of unknown function DUF699 ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
   
  
 0.738
Huta_0226
PFAM: PUA domain containing protein; SMART: PUA domain containing protein; KEGG: hma:rrnAC0210 putative RNA binding protein.
 
   
 0.703
rlmE
Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
   
  
 0.703
Huta_1249
PFAM: putative RNA methylase; Methyltransferase type 11; KEGG: hma:rrnAC2834 putative RNA methylase.
  
  
 0.657
Huta_2405
PFAM: PP-loop domain protein; KEGG: hma:rrnAC2005 hypothetical protein.
 
  
 0.655
Huta_1159
PFAM: GTP-binding protein HSR1-related; Nucleolar GTP-binding-1 domain protein; KEGG: hma:rrnAC2374 GTP-binding protein.
  
    0.652
Your Current Organism:
Halorhabdus utahensis
NCBI taxonomy Id: 519442
Other names: H. utahensis DSM 12940, Halorhabdus utahensis AX-2, Halorhabdus utahensis DSM 12940, Halorhabdus utahensis str. DSM 12940, Halorhabdus utahensis strain DSM 12940
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