STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Huta_1284TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: hma:rrnAC1517 anthranilate synthase component II. (207 aa)    
Predicted Functional Partners:
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.999
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 0.999
Huta_2480
TIGRFAM: para-aminobenzoate synthase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: hma:rrnAC0709 anthranilate synthase component I.
 0.999
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: hma:rrnAC1886 indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
 0.994
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: hma:rrnAC1519 N-(5'- phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
  
 0.988
Huta_1762
PFAM: glycosyl transferase family 3; KEGG: hwa:HQ3122A anthranilate phosphoribosyltransferase.
 
 0.980
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.952
Huta_3024
PFAM: Chorismate mutase; KEGG: hma:rrnAC0752 hypothetical protein.
    
 0.927
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.922
Huta_0814
TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: hma:rrnAC0837 menaquinone-specific isochorismate synthase.
 
 
  0.920
Your Current Organism:
Halorhabdus utahensis
NCBI taxonomy Id: 519442
Other names: H. utahensis DSM 12940, Halorhabdus utahensis AX-2, Halorhabdus utahensis DSM 12940, Halorhabdus utahensis str. DSM 12940, Halorhabdus utahensis strain DSM 12940
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